Nine genes were identified overexpressed in both basal-like breast cancer cells and BRCA1 mutated cells. ITPK1, 1.982, 0.536, CENPN, 2.008, 0.964.

cf) Tissue ID[Tissue type]: BLCA[Bladder Urothelial Carcinoma], BRCA[Breast invasive carcinoma], CESC[Cervical squamous cell carcinoma and endocervical adenocarcinoma], COAD[Colon adenocarcinoma], GBM[Glioblastoma multiforme], Glioma Low Grade, HNSC[Head and Neck squamous cell carcinoma], KICH[Kidney Chromophobe], KIRC[Kidney renal clear cell carcinoma], KIRP[Kidney renal papillary cell

Inositol-tetrakisphosphate 1-kinase is an enzyme that in humans is encoded by the ITPK1 gene.. It is involved in inositol signalling pathways which regulate the conductance of calcium-activated chloride channels, and therefore could be relevant in the study of cystic fibrosis. ITPK1 mutation reduces labeling of InsP 6 by 50%, with concomitant accumulation of d / l ‐Ins(3,4,5,6)P 4, but because it does so without affecting the level of Ins(1,3,4,5,6)P 5 (Figures 5a and S6a) suggests that ITPK1 probably does not act as an Ins(1,3,4,5,6)P 5 1‐phosphatase. 1 1Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Lymphoma, Peking University Cancer Hospital & Institute, 52 Fucheng Road, Haidian District, Beijing, 100142 People's Republic of China.

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Simultaneous expression of ITPK1 with the inositol kinase TK2285 in plc∆isc1∆ yeast strain restored the IP 6 level (Fig. 4C), which confirmed that ITPK1 can use I(3)P 1 both in vitro and in vivo. Immune Thrombocytopenia. I. What every physician needs to know. Immune Thrombocytopenia (ITP) in the past has been called Idiopathic Thrombocytopenia Purpura and Immune Thrombocytopenic Purpura. The risk score system based on the green module [including ITPK1 antisense RNA 1 (ITPK1-AS1), KCNQ1 downstream neighbor (KCNQ1DN), long intergenic non-protein coding RNA 167 (LINC00167), LINC00173 and LINC00307] was the more efficient at predicting risk compared with those based on the turquoise, or the green + turquoise modules. ITPK1 (inositol-tetrakisphosphate 1-kinase) Non-annotated gene.

Fallopian tube exhibited additional membranous staining. Immune Thrombocytopenia. I. What every physician needs to know.

Get information and answers to common questions about cancer from the American Cancer Society. What patients and caregivers need to know about cancer, coronavirus, and COVID-19. Whether you or someone you love has cancer, knowing what to ex

Mouse gene. Mouse insertional mutagenesis experiments support the designation of ITPK1 as a cancer causing gene. More information.

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Oncogene 1. Tumor Suppressor gene 2.

Fallopian tube exhibited additional membranous staining. Immune Thrombocytopenia. I. What every physician needs to know. Immune Thrombocytopenia (ITP) in the past has been called Idiopathic Thrombocytopenia Purpura and Immune Thrombocytopenic Purpura. (e.g. HGVST307, rs2317951, Pancreatic cancer, Todd JA, ADAM19, chr12:13234..4534534, 77 Study Datasets reported containing markers in gene or region ITPK1 Summary of ITPK1 expression in human tissue. Cytoplasmic expression in several different tissue types, including CNS. Gene information about ENSG00000100605 / ITPK1 - inositol-tetrakisphosphate 1-kinase ITPK1-Dependent Inositol Polyphosphates Regulate Auxin Responses inArabidopsis thaliana ABSTRACT The combinatorial phosphorylation of myo-inositol results in the generation of different inositol phosphates (InsP), of which phytic acid (InsP 6 ) is the most abundant species in eukaryotes.
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Inositol-tetrakisphosphate 1-kinase. High.

Curated gene. This is NOT an expert curated gene .
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This gene does not have a cancer hallmark. You can see more information about hallmarks. COSMIC gene ITPKB (COSG226) Genomic coordinates 1:226631690..226739175

This is NOT an expert curated gene . Mouse gene. Mouse insertional mutagenesis experiments support the designation of ITPK1 as a cancer causing gene. More information. Hallmark gene.